A prostatespecific antigen, distinct from acid phosphatase, was identified by immunologic procedures in prostate tissues normal, benign hypertrophic, and cancerous and seminal plasma, as well as in sera of patients with prostatic cancer and of nude mice bearing human prostatic tumor. A new paper from researchers at harvard university confirms earlier evidence that exercise is protective against prostate cancer mortality. Prostate cancer is usually diagnosed in the early stages. Find another journal best suited to publish your research. Docetaxel is an antineoplastic chemotherapy drug, classified as a plant alkaloid, a taxane and an antimicrotubule agent. Racial variation is also pronounced, with black men of african ancestry in the usa having 58% greater incidence and 144%.
The incidence of this disease is highest among caucasian and africanamerican males, with reported incidences of. To diagnose prostate cancer, you doctor may do a digital rectal. Prostate cancer and prostatic diseases covers all aspects of prostatic diseases, in particular prostate cancer overcoming barriers to performing transperineal prostate biopsies editorial much of the push to perform transperineal prostate biopsy has been driven by concerns about increasing rates of sepsis associated with the transrectal. The advances that have been made in detecting prostate cancer have led to. It is published four times per year, march 30, june 30, september 30. Risk factors for developing prostate cancer include being over 65 years of age, family history, and being africanamerican. Prostate cancer is rare in men younger than 40, but the chance of having prostate cancer rises rapidly after age 50. An international journal in cancer research and oncology.
Department of plant pathology, bangladesh agricultural university, mymensingh, bangladesh close. Serinearginine protein kinase 1 srpk1, a determinant of angiogenesis, is upregulated in prostate cancer and correlates with disease stage and invasion nicholas bullock, jonathan potts, andrew j simpkin, anthony koupparis, steve j harper, jon oxley, sebastian oltean. Agespecific prostate cancer incidence and treatment data from the national cancer institutes surveillance, epidemiology, and end results program and agespecific population estimates from the us census were used to estimate the excess number of men diagnosed and treated each year after the introduction of prostatespecific antigen screening. Eighty per cent of men did not know the function of the prostate, and 48% failed to identify prostate cancer as the most common internal cancer in men. Full text in epub is free except for the current issue. Advances in radiotherapy for prostate cancer treatment. Raceethnicity prostate cancer develops more often in africanamerican men and in caribbean men of african ancestry than in men of other races. In a study in the journal cancer, researchers at duke university medical center and elsewhere analyzed the records of 1,319 men who had their prostates removed between 1988 and 2008 and found that 304 of them had a rising psa level after surgery, which generally indicates that the cancer has reoccurred and spread. New england journal of medicine letter calls prostate cancer screening guidelines into question newyorkpresbyterian and weill cornell medicine urologists urge reconsideration of prostate cancer. In 1997 more than 209 900 american men were diagnosed with prostate cancer and more than 41 800 died from the. May 16, 2017 in this special theme issue of the world journal of urology, we explore several aspects of prostate cancer global epidemiology in detail. Questionnaires administered by general practitioners in five general practices in the perth metropolitan and regional areas of western australia. Active monitoring as effective as surgery over 10 years. New england journal of medicine letter calls prostate.
Age and family his tory are the main risk factors find, read and cite all the research. List of books and articles about prostate cancer online. The incidence has risen in recent decades, mainly fuelled by more widespread use of prostatespecific antigen psa testing, although prostate cancer mortality rates have remained relatively static over that time period. Early stage prostate cancer n695 deaths at median 8. Only 25% of cancers are diagnosed before the age of 65y in europe 1. Knowledge and attitudes of men about prostate cancer, and predictors of knowledge. Prostate cancer is one of the most common cancers in men, and there are a number of management options for localized disease, such as active surveillance, radical prostatectomy, chemotherapy, intensitymodulated radiotherapy, radiofrequency ablation, cryotherapy, stereotactic ablative radiotherapy, particle therapy, brachytherapy, and an emerging range of focal therapies. Prostate cancer provides a multidisciplinary platform for scientists, surgeons, oncologists and clinicians working on prostate cancer. An estimated 174,650 new cases of prostate cancer will be diagnosed in 2019, accounting for 20% of new cancer cases in men. Prostate cancer in primary care pubmed central pmc. This readership is 10 times more when compared to other subscription journals source.
Prostate cancer is the second most common cause of cancer deaths in men in most developed countries, and the incidence has increased significantly over recent years. Journal of clinical pathology may 2017, 70 5 383389. The prostate is about the size of a walnut and lies just behind the urinary bladder. Biopsy, a cancer journal entry by robert vaughn young. More advanced clinically then current us patients only 5% of men had screen detected pc advantage largely in men journal of medicine found that regardless of treatment methods, the risk of dying from early prostate cancer in the next 10 years is low and nearly identical. Prostate cancer diagnosis memorial sloan kettering. The incidence rates of both diseases are currently showing a tendency to increase. Articles from prostate cancer are provided here courtesy of hindawi publishing corporation. Srpk1, a determinant of angiogenesis, is upregulated in prostate cancer and correlates with disease stage and invasion. About 6 in 10 cases of prostate cancer are found in men older than 65. Prostate cancer centre a community based outreach clinic, the prostate cancer centre is a partnership between the london hospitals, and hosts cancer prevention trials, patient education sessions and well followup clinics. This is one of several essays from my private cancer journal. Cancer research is basic research into cancer in order to identify causes and develop strategies for prevention, diagnosis, treatments and cure. Pdf prostate cancer is the most frequent tumor found in men worldwide and in mexico in particular.
Prostate cancer prostate cancer symptoms medlineplus. Prostate cancerincidence and mortality deathrates by race, indiana, 20052014 prostate cancer is an uncontrolled growth and spread of cells in the prostate, an exocrine gland in the male reproductive system. The 4kscore test is a blood test that delivers a patientspecific risk score for having aggressive prostate cancer. In the past few years, regular prostate cancer screening specifically the psa blood test has gone from being the standard to being scorned. It occurs predominantly in men 65 years of age and older. Biopsy, a prostate cancer journal entry by robert vaughn young. Prostate cancer is the most common cancer in men after skin cancer.
A prostate specific antigen, distinct from acid phosphatase, was identified by immunologic procedures in prostate tissues normal, benign hypertrophic, and cancerous and seminal plasma, as well as in sera of patients with prostatic cancer and of nude mice bearing human prostatic tumor. Prostate cancer is diagnosed by digital rectal exam, prostate specific antigen psa test, and prostate biopsy. Knowledge and attitudes of men about prostate cancer the. This test can help reduce the number of unnecessary biopsies by providing information to improve decisionmaking before ordering a prostate biopsy. Prostate cancer is a common malignancy seen worldwide. Oct 07, 2009 agespecific prostate cancer incidence and treatment data from the national cancer institutes surveillance, epidemiology, and end results program and agespecific population estimates from the us census were used to estimate the excess number of men diagnosed and treated each year after the introduction of prostate specific antigen screening.
Q1 green comprises the quarter of the journals with the highest values, q2 yellow the second highest values, q3 orange the third highest values and q4 red the lowest values. The set of journals have been ranked according to their sjr and divided into four equal groups, four quartiles. In this special theme issue of the world journal of urology, we explore several aspects of prostate cancer global epidemiology in detail. Epidemiology of prostate cancer and benign prostatic hyperplasia jmaj 526. Prostate cancer treatment study changing the way doctors practice. This emedtv health channel offers a wide range of articles on the subject and also explains how to navigate the page to find the information you need. Prostate cancer journal articles brca1 and brca2 gene mutations and colorectal cancer risk a large metaanalysis finds that carriers of brca1 mutation have an increased risk of colorectal cancer. The discovery of smallmolecule anticancer drugs, which target specific oncogenic driver mutations, dramatically changed the clinical therapeutic modality pdf. The prostate is the gland below a mans bladder that produces fluid for semen. It serves as an international medium for these studies, presenting comprehensive coverage of clinical, anatomic, embryologic, physiologic, endocrinologic, and biochemical studies. Rage is the cranking up of the roller coaster, clack, clack, clack, as i am taken higher, the rage that this should happen to me clack, clack, clack, higher and higher.
Prostate cancer causes, risk factors, and prevention. Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate and compare applications of the various cancer treatment. Prostate cancer is one of the most malignancies in men in the united states, second only to skin cancer, and as a cause of cancer death in men is second only to lung cancer. Prostate cancer treatment study changing the way doctors. Epidemiology of prostate cancer and benign prostatic hyperplasia. In this new study published in the october 2018 issue of european urology, men who engaged most frequently in vigorous activities had a 30% lower risk of advanced prostate cancer, a 25% lower risk of developing advanced prostate cancer, and a 25% lower. Pdf epidemiology, etiology, diagnosis and treatment of. Risk factors include age, family history, ethnicity, and diet. University of texas health science center at san antonio. Epidemiology of prostate cancer and benign prostatic. More advanced clinically then current us patients only 5% of men had screen detected pc advantage largely in men in the prostate, an exocrine gland in the male reproductive system. Nicholas bullock, jonathan potts, andrew j simpkin, anthony koupparis. Along with the testicles and the seminal vesicles, the prostate secretes the fluid that makes up semen. In unscreened populations prostate cancer has the steepest ageincidence curve of all cancers and increases at approximately the 6 th power of age.
Prostate cancer is a malignancy of one of the major male sex glands. The prostate health index phi is a new combination of three blood tests that. In some men, it will be advanced when it is first diagnosed. There are many studies currently being conducted to help further understand how diet and prostate cancer are related. Symptoms may include frequent need to urinate, incontinence, pain, blood in the urine, fatigue, and more. Prostate cancer journal articles worldwide trends in penile implantation surgery a new study examines the global trends in penile prosthesis implantation in recent years. Good nutrition may reduce the incidence of prostate cancer and help reduce the risk of prostate cancer progression. It is not intended as anything than a record of my states of mind as i struggled with the disease and the effects of the treatment.
Prostate cancer journal articles worldwide trends in penile implantation surgery a new study examines the global trends in penile prosthesis implantation in. Prostate cancer is characterized by uncontrolled growth of cells in the prostate gland. To ascertain the current level of understanding among older men about prostate cancer, including treatment options and their potential side effects. Rage is what fuels all the reading i have been doing about prostate cancer in the days that followed the diagnosis.
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